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ACROBiosystems Mouse LILRB4 / CD85k / ILT3 Protein, Fc Tag
544.34 € - 3060.43 €
Spezifikation
| Zugriffsnummer | NP_038560.1 |
|---|---|
| Molekulargewicht | 50.7 kDa |
| Quelle | Mouse LILRB4, Fc Tag (CDK-M5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Lys 238 (Accession # Q64281-1). |
| Immunogen | Gly 24 - Lys 238 |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15846417
|
ACROBiosystems
CDK-M5250-100UG |
100 μg |
544.34 €
100 Mikrogramm |
Verfügbar ab: 06-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
16497379
|
ACROBiosystems
CDK-M5250-1MG |
1 mg |
3060.43 €
1 Milligramm |
Verfügbar ab: 06-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. As a result of glycosylation, the protein migrates as 60-66 kDa under reducing (R) condition, and 120-140 kDa under non-reducing (NR) condition (SDS-PSpezifikation
| NP_038560.1 | |
| Mouse LILRB4, Fc Tag (CDK-M5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Lys 238 (Accession # Q64281-1). | |
| -20°C | |
| LILRB4 | |
| Mouse | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 50.7 kDa | |
| Gly 24 - Lys 238 | |
| LILRB4,ILT3,LIR5,CD85K,HM18 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |