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NBI 35965 hydrochloride, Tocris Bioscience™

Potent and selective CRF1 antagonist

Marke:  Tocris (Bio-Techne) 310010

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 10mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13412444

  • 211.20 € / 10 Milligramm


Voraussichtlicher Liefertermin 24-04-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Potent and selective corticotropin-releasing factor receptor 1 (CRF 1 ) antagonist (K i values are 4 and > 10000 nM at CRF 1 and CRF 2 respectively). Inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro (pIC 50 values are 7.1 and 6.9 respectively) and attenuates CRF and ACTH production in vivo. Orally active and brain penetrant with anxiolytic activity.
Spezifikation

Chemische Identifikatoren

603151-83-3
437.793
nbi 35965 hydrochloride, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-4-methyl-7,8-dihydro-6h-1,3,6,8a-tetraazaacenaphthylene-hydrogen chloride 1/1, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-7,8-dihydro-4-methyl-6h-1,3,6,8a-tetraazaacenaphthylene hydrochloride
CCC1CN2C3=C(C(=N2)C4=C(C=C(C=C4)Cl)Cl)N=C(C=C3N1CC5CC5)C.Cl
C21H23Cl3N4
LNYUWBPFYXPUIO-RSAXXLAASA-N
71433630

Spezifikation

NBI 35965 hydrochloride
603151-83-3
nbi 35965 hydrochloride, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-4-methyl-7,8-dihydro-6h-1,3,6,8a-tetraazaacenaphthylene-hydrogen chloride 1/1, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-7,8-dihydro-4-methyl-6h-1,3,6,8a-tetraazaacenaphthylene hydrochloride
CCC1CN2C3=C(C(=N2)C4=C(C=C(C=C4)Cl)Cl)N=C(C=C3N1CC5CC5)C.Cl
71433630
>98%
10mg
C21H23Cl3N4
LNYUWBPFYXPUIO-RSAXXLAASA-N
437.793
437.79
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