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NOTCH3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 55114-1-AP-150UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886565

  • 329.85 € / 150 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

The antibody is specific to NOTCH3.

NOTCH3 is the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal domit arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Spezifikation

Spezifikation

NOTCH3
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q61982, Q9UM47
CADASIL, CASIL, Notch 3, Notch homolog 3 (Drosophila), NOTCH3
Rabbit
IgG
150 μL
-20°C
Primary
18131, 4854
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
NOTCH3
Liquid
Notch3
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation