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Tocris Bioscience™ NSC 23766
Selective inhibitor of Rac1-GEF interaction; antioncogenic
N.V.
Spezifikation
| Produkttyp | NSC 23766 |
|---|---|
| Molekulargewicht | 530.97 |
| Hemmstoffe | Rho GTPase Inhibitors |
Beschreibung
Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ∽ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotypes in prostate cancer cells.Spezifikation
| NSC 23766 | |
| 530.97 | |
| Rho GTPase Inhibitors |
For Research Use Only