missing translation for 'onlineSavingsMsg'
Learn More

NUMB Mouse anti-Human, Mouse, Rat, Clone: 2G12B7, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 60137-1-IG-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 16887105

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 23-06-2021

Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!


Beschreibung

Beschreibung

Four transcript variants encoding different isoforms have been found for this gene. The antibody can bind to all these four isoforms P65, P66, P71, and P72, but can not recognize NUMBL.

Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Spezifikation

Spezifikation

NUMB
2G12B7
Unconjugated
NUMB
Liquid
Numb
peptide
Caprylic Acid Precipitation
RUO
Antibody
Monoclonal
Mouse, Human, Rat
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P49757, Q2LC84, Q9QZS3
h Numb, NUMB, numb homolog (Drosophila), Protein numb homolog, Protein S171, S171
Mouse
IgG2a
20 μL
-20°C
Primary
18222, 29419, 8650
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate