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NUMB Mouse anti-Human, Mouse, Rat, Clone: 2G12B7, Proteintech
Mouse Monoclonal Antibody
129.00 € - 349.00 €
Spezifikation
Antigen | NUMB |
---|---|
Klon | 2G12B7 |
Konzentration | 2 mg/mL |
Anwendungen | Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry |
Klassifikation | Monoclonal |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16887105
|
Proteintech
60137-1-IG-20UL |
20 μL |
129.00 €
20 Mikroliter |
Verfügbar ab: 29-04-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
16877105
|
Proteintech
60137-1-IG-150UL |
150 μL |
349.00 €
150 Mikroliter |
Verfügbar ab: 29-04-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Four transcript variants encoding different isoforms have been found for this gene. The antibody can bind to all these four isoforms P65, P66, P71, and P72, but can not recognize NUMBL.
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.Spezifikation
NUMB | |
2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
h Numb, NUMB, numb homolog (Drosophila), Protein numb homolog, Protein S171, S171 | |
Numb | |
IgG2a | |
Caprylic Acid Precipitation | |
Antibody |
2G12B7 | |
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
Unconjugated | |
Mouse | |
Mouse, Human, Rat | |
P49757, Q2LC84, Q9QZS3 | |
18222, 29419, 8650 | |
peptide | |
Primary | |
-20°C | |
NUMB |