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PD 0325901, Tocris Bioscience™

Potent inhibitor of MEK1/2

Marke:  Tocris (Bio-Techne) 419210

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 10mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13414324

  • 332.65 € / 10 Milligramm


Voraussichtlicher Liefertermin 01-08-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Potent MEK1 and MEK2 inhibitor. Inhibits MEK activity in mouse colon 26 cells (IC50 = 0.33 nM). Inhibits the growth of melanoma cell lines in vitro and in vivo; induces G1-phase cell cycle arrest and apoptosis in a mouse xenograft model. Also inhibits production of proangiogenic cytokines such as VEGF. Enhances generation of induced pluripotent stem cells (iPSCs). Orally active.
Spezifikation

Chemische Identifikatoren

391210-10-9
482.198
r-n-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, r-n-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenylamino benzamide, unii-86k0j5ak6m, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-2r-2,3-dihydroxypropyl oxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-r-2,3-dihydroxy-propoxy-3,4-difluoro-2-2-fluoro-4-iodo-phenylamino-benzamide, n-r-2,3-dihydroxypropyl oxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodoanilino benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino-benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodo-anilino benzamide
N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
C16H14F3IN2O4
SUDAHWBOROXANE-SECBINFHSA-N
9826528
C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O

Spezifikation

PD 0325901
391210-10-9
r-n-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, r-n-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenylamino benzamide, unii-86k0j5ak6m, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-2r-2,3-dihydroxypropyl oxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-r-2,3-dihydroxy-propoxy-3,4-difluoro-2-2-fluoro-4-iodo-phenylamino-benzamide, n-r-2,3-dihydroxypropyl oxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodoanilino benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodophenyl amino-benzamide, n-2r-2,3-dihydroxypropoxy-3,4-difluoro-2-2-fluoro-4-iodo-anilino benzamide
C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
482.198
482.19
10mg
C16H14F3IN2O4
SUDAHWBOROXANE-SECBINFHSA-N
N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
9826528
>99%
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