missing translation for 'onlineSavingsMsg'
Learn More

PG 01, Tocris Bioscience™

CFTR potentiator; corrects F508del-CFTR conductance defect

Marke:  Tocris (Bio-Techne) 394350

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13413864

  • 691.16 € / 50 Milligramm


Voraussichtlicher Liefertermin 20-02-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. Corrects gating defects of CFTR mutants such as ΔF508 (Ka = 0.3μM), E193K and G970R (Kd values are 0.22μM and 0.45μM respectively). Increases ΔF508-CFTR Cl- currents in the presence of forskolin; displays no effect on Ca2+-activated Cl- current.
Spezifikation

Chemische Identifikatoren

853138-65-5
439.559
phenylglycine-01, 2-2-1h-indol-3-yl-acetyl-methylamino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-yl-n-methylacetamido-n-4-isopropylphenyl-2-phenylacetamide, d03pgv, pg hplc, n-methyl-n-2-4-1-methylethyl phenyl amino-2-1h-indole-3-acetamide, 2-1h-indol-3-ylacetyl methyl amino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-ylacetyl methylamino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-yl acetyl-methylamino-2-phenyl-n-4-propan-2-ylphenyl acetamide, 2-2-1h-indol-3-yl-n-methylacetamido-2-phenyl-n-4-propan-2-yl phenyl acetamide
2-[[2-(1H-indol-3-yl)acetyl]-methylamino]-2-phenyl-N-(4-propan-2-ylphenyl)acetamide
C28H29N3O2
PQAYCXMQTUEDRD-UHFFFAOYSA-N
4695397
CC(C)C1=CC=C(C=C1)NC(=O)C(C2=CC=CC=C2)N(C)C(=O)CC3=CNC4=CC=CC=C43

Spezifikation

PG 01
853138-65-5
phenylglycine-01, 2-2-1h-indol-3-yl-acetyl-methylamino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-yl-n-methylacetamido-n-4-isopropylphenyl-2-phenylacetamide, d03pgv, pg hplc, n-methyl-n-2-4-1-methylethyl phenyl amino-2-1h-indole-3-acetamide, 2-1h-indol-3-ylacetyl methyl amino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-ylacetyl methylamino-n-4-isopropylphenyl-2-phenylacetamide, 2-2-1h-indol-3-yl acetyl-methylamino-2-phenyl-n-4-propan-2-ylphenyl acetamide, 2-2-1h-indol-3-yl-n-methylacetamido-2-phenyl-n-4-propan-2-yl phenyl acetamide
CC(C)C1=CC=C(C=C1)NC(=O)C(C2=CC=CC=C2)N(C)C(=O)CC3=CNC4=CC=CC=C43
439.559
439.55
50mg
C28H29N3O2
PQAYCXMQTUEDRD-UHFFFAOYSA-N
2-[[2-(1H-indol-3-yl)acetyl]-methylamino]-2-phenyl-N-(4-propan-2-ylphenyl)acetamide
4695397
>98%
Videos