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Invitrogen™ Phospho-CDK2 (Thr160) Polyclonal Antibody
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Código de producto. 16366614
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Menge:
100 μL
Tamaño de la unidad:
100 Mikroliter
Código de producto. Menge unitSize
16366614 100 μL 100 Mikroliter
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Código de producto. 16366614

Marca: Invitrogen™ PA577906

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Descripción

Rabbit Polyclonal Antibody

Positive Control: 293T, HeLa, HeLa (10 mM Hydroxyurea treatment for 18 hr) Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Chicken (100%), Sheep (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
TRUSTED_SUSTAINABILITY

Especificaciones

Antigen Phospho-CDK2 (Thr160)
Anwendungen Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Konzentration 3.35 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gen CDK2
Gen-Zugriffsnummer P24941
Gen-Alias A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Gensymbole CDK2
Wirtsspezies Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding phospho Thr160 of human CDK2. The exact sequence is proprietary.
Reinigungsverfahren Antigen affinity chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 1017
Zielspezies Human
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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