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Invitrogen™ Phospho-HDAC5 (Ser259) Polyclonal Antibody
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Product Code. 16671485
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Menge:
100 μL
Unit Size:
100 Mikroliter
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16671485 100 μL 100 Mikroliter
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Product Code. 16671485 Supplier Invitrogen™ Supplier No. PA5105040

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HDAC5 only when phosphorylated at Serine 259.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC5 (Ser259)
Anwendungen Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gen HDAC5
Gen-Zugriffsnummer Q9UQL6, Q9Z2V6
Gen-Alias AI426555; Antigen NY-CO-9; DKFZp779K1053; FLJ90614; HD5; HD7; HD7b; HD9; HDAC; Hdac4; HDAC5; HDAC-5; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4; histone deacetylase 5; histone deacetylase mHDA1; KIAA0600; KIAA0744; mHDA1; mKIAA0600; NY-CO-9
Gensymbole HDAC5
Wirtsspezies Rabbit
Immunogen A synthesized peptide derived from human HDAC5(Accession Q9UQL6), corresponding to amino acid residues around phosphorylated Ser259.
Reinigungsverfahren Sequential chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 10014, 15184
Zielspezies Human, Mouse
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Liquid
Isotype IgG
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