missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Phospho-PI3K p85/p55 (Tyr467, Tyr199) Polyclonal Antibody, Invitrogen™
Beschreibung
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50kDa. It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1.
Spezifikation
Spezifikation
| Antigen | Phospho-PI3K p85/p55 (Tyr467, Tyr199) |
| Anwendungen | Immunocytochemistry, Immunofluorescence, Western Blot |
| Klassifikation | Polyclonal |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | PIK3R3 |
| Gen-Zugriffsnummer | P27986, Q92569, P26450, Q64143, Q63787, Q63789 |
| Gen-Alias | Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-al, RP4-533D7.2, p55, p55-GAMMA, 100% homology to SWISS-PROT Q92569, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, PI3K regulatory subunit gamma, p55PIK, phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma), phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma), phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 |
| Gensymbole | PIK3R1, PIK3R3 |
| Mehr anzeigen |
Name des Produkts
Indem Sie auf Absenden klicken, erklären Sie sich damit einverstanden, dass Fisher Scientific sich mit Ihnen in Verbindung setzen kann, um Ihr Feedback in diesem Formular zu bearbeiten. Wir werden Ihre Informationen nicht für andere Zwecke weitergeben. Alle bereitgestellten Kontaktinformationen werden in Übereinstimmung mit unserer Datenschutzrichtlinie aufbewahrt. Datenschutzrichtlinie.
Haben Sie Verbesserungsvorschläge?