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Invitrogen™ Phospho-TrkC (Tyr516) Polyclonal Antibody

Beschreibung
This antibody is predicted to react with mouse and rat based on sequence homology.
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
Spezifikation
Spezifikation
| Antigen | Phospho-TrkC (Tyr516) |
| Anwendungen | ELISA, Immunohistochemistry, Western Blot |
| Klassifikation | Polyclonal |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | Ntrk3 |
| Gen-Zugriffsnummer | Q03351, Q16288, Q6VNS1 |
| Gen-Alias | AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C |
| Gensymbole | Ntrk3 |
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