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PI4K2A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00 € - 399.00 €
Spezifikation
Antigen | PI4K2A |
---|---|
Konzentration | 0.13 mg/mL |
Anwendungen | Western Blot |
Klassifikation | Polyclonal |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16894444
|
Proteintech
15318-1-AP-20UL |
20 μL |
140.00 €
20 Mikroliter |
Verfügbar ab: 23-04-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
16884444
|
Proteintech
15318-1-AP-150UL |
150 μL |
399.00 €
150 Mikroliter |
Verfügbar ab: 23-04-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4KII RNAi had little effect on intra-Golgi trafficking, but it inhibited export to plasma membrane export by 35%. It has been proposed that PI4KII generates PtdIns4P-rich domains within the Golgi that specify docking of the AP1 coat machinery.Spezifikation
PI4K2A | |
Western Blot | |
Unconjugated | |
Rabbit | |
Rat, Mouse, Human | |
Q2TBE6, Q99M64, Q9BTU6 | |
114554, 55361, 84095 | |
PI4K2A Fusion Protein Ag7564 | |
Primary | |
-20°C | |
PI4K2A |
0.13 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
PI 4-kinase II alpha, PI4K2A, PI4KII, PIK42A, RP11 548K23.6 | |
PI4K2A | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |