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Invitrogen™ PPAR gamma Polyclonal Antibody
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Artikelnummer. 10794655
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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10794655 100 μL 100 Mikroliter
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Artikelnummer. 10794655 Lieferant Invitrogen™ Lieferanten-Nr. PA3821A

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Beschreibung

Rabbit Polyclonal Antibody

PA3-821A detects peroxisome proliferator activated receptor (PPAR) gamma from human and mouse samples. This antibody is a reproduction of PA3-821, using the same immunizing peptide and new host rabbits. PA3-821A has been successfully used in IF and Western blot procedures. Previous batches of this antibody have been used in gel shift, immunocytochemistry, and immunofluoresence procedures. By Western blot, this antibody detects a 57 kDa protein representing PPAR gamma 2 from differentiated mouse 3T3-L1 cell lysate. Immunolocalization of previous batches gives predominant nuclear staining. The PA3-821A immunizing peptide corresponds to amino acid residues 284-298 from mouse PPAR gamma 2. This sequence is completely conserved in PPAR gamma 1, but exhibits no significant homology with PPAR alpha or NUC1. This sequence is completely conserved in mouse, human, and rat.

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen PPAR gamma
Anwendungen Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Konzentration Conc. Not Determined
Konjugat Unconjugated
Zusammensetzung Whole serum with 0.05% sodium azide
Gen PPARG
Gen-Zugriffsnummer O88275, P37231, P37238
Gen-Alias CIMT1; GLM1; HUMPPARG; NR1C3; nuclear hormone receptor; nuclear hormone receptor; PPARG; Nuclear receptor subfamily 1 group C member 3; nuclear receptor transcription factor; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferative activated receptor, gamma; peroxisome proliferative activated receptor, gamma-2; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 1; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activated receptor gamma-1; peroxisome proliferator activated receptor gamma-2; peroxisome proliferator activatived receptor gamma; peroxisome proliferator activator receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor gamma 1a; peroxisome proliferator-activated receptor gamma 1-a; peroxisome proliferator-activated receptor gamma 1b; peroxisome proliferator-activated receptor gamma 1-b; peroxisome proliferator-activated receptor gamma 1c; peroxisome proliferator-activated receptor gamma 1d; peroxisome proliferator-activated receptor gamma 2; peroxisome proliferator-activated receptor-gamma; peroxisome proliferator-activated receptor-gamma 2; peroxisome proliferator-cctivated receptor gamma 1; PPAR gamma; PPAR gamma 1; PPAR gamma 3; Pparg; PPARG1; PPARG2; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2; PPARy; proliferator activated gamma; transcription factor
Gensymbole PPARG
Wirtsspezies Rabbit
Immunogen Synthetic peptide corresponding to residues M(284) M G E D K I K F K H I T P L(298) of mouse PPAR gamma 2.
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 19016, 25664, 5468
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotype IgG
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