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PPBP Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Código de producto. 17814323
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Menge:
2 x 500μg
25 μg
50 μg
500 μg
Tamaño de la unidad:
1 Milligramm
25 Mikrogramm
50 Mikrogramm
500 Mikrogramm
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Código de producto. Menge unitSize
17814323 2 x 500μg 1 Milligramm
17833913 25 μg 25 Mikrogramm
17883953 50 μg 50 Mikrogramm
30054392 500 μg 500 Mikrogramm
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Código de producto. 17814323 Proveedor Invitrogen N.º de proveedor 500P03BT1MG

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Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human NAP-2 (CXCL7). Anti-Human NAP-2 (CXCL7)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human NAP-2 by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human NAP-2 (CXCL7) (500-P03) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human NAP-2. Western Blot: To detect Human NAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible development reagents the detection limit for Recombinant Human NAP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P03BT-1MG will be provided as 2 x 500 μg

Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils. The platelet basic protein (PBP), a member of the a-chemokine family, resides in the a-granules of platelets and is released upon their activation. Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2). PBP and its N-truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The gene encoding human PBP maps to chromosome 4q12-q13.
TRUSTED_SUSTAINABILITY

Especificaciones

Antigen PPBP
Anwendungen ELISA, Western Blot
Klassifikation Polyclonal
Konzentration 0.1-1.0 mg/mL
Konjugat Biotin
Zusammensetzung PBS with no preservative
Gen PPBP
Gen-Zugriffsnummer P02775
Gen-Alias 2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB; THBGB1; thrombocidin 1; thrombocidin 2; thromboglobulin, beta-1
Gensymbole PPBP
Wirtsspezies Rabbit
Immunogen E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)
Reinigungsverfahren Antigen affinity chromatography
Menge 2 x 500μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 5473
Zielspezies Human
Inhalt und Lagerung -20°C
Form Lyophilized
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