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PPP6C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 15852-1-AP-150UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16885224

  • 329.85 € / 150 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5′ to 3′ exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5′ and 3′ overhangs and hairpins. These activities are essential for V(D)J recombination and for the 5′ and 3′ overhang processing in nonhomologous DNA end joining.
Spezifikation

Spezifikation

PPP6C
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O00743, Q64620, Q9CQR6
PP6C, PPP6, PPP6C
Rabbit
IgG
150 μL
-20°C
Primary
171121, 5537, 67857
Immunoprecipitation, Western Blot
Unconjugated
PPP6C
Liquid
Ppp6c
PPP6C Fusion Protein Ag8670
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation