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PTPRO Mouse anti-Human, CoraLite 488, Clone: 2F2B4, Proteintech
Mouse Monoclonal Antibody
Marke: Proteintech CL488-67000-100UL
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
PTPRO(receptor-type tyrosine-protein phosphatase O) is also named as GLEPP1, PTPU2 and belongs to the protein-tyrosine phosphatase family. The protein is a receptor-like membrane protein tyrosine phosphatase expressed at the apical membrane of the podocyte foot processes in the kidney(PMID:21722858). The 1,159-amino acid predicted mature protein contains a large extracellular domain, a single transmembrane domain, and a single intracellular PTPase domain. Defects in PTPRO are the cause of nephrotic syndrome type 6 (NPHS6). In reducing conditions, PTPRO can form a smear from 180 to 220 kDa; In non-reducing conditions, a band appeares around 350 kDa, which likely represents the dimeric form of full-length PTPRO (PMID: 19573017).
Spezifikation
| PTPRO | |
| Monoclonal | |
| 1000 μg/mL | |
| Mouse | |
| Primary | |
| Human, Mouse, Rat | |
| IgG2b |
| Immunofluorescence | |
| 2F2B4 | |
| CoraLite 488 | |
| 100 μL | |
| 5800 | |
| Liquid |