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Tocris Bioscience™ (R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™

KDM4A inhibitor; also NF-κB activator

Marke:  Tocris Bioscience™

Weitere Details : CAS : 103404-90-6 Netto-Gewicht : 0.00970kg

Artikelnummer. 18761348

  • 163.06 € / 50 Milligramm
Verfügbar ab: 22-07-2024
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Beschreibung

Beschreibung

(R)-2-Hydroxyglutaric acid disodium salt is an oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells and inhibits FTO (mRNA N6-methyladenine demethylase).
Spezifikation

Spezifikation

(R)-2-Hydroxyglutaric acid disodium salt
(R)-2-Hydroxypentanedioic acid disodium salt
Soluble to 100mM in water
192.08
White
103404-90-6
50 mg
C5H6Na2O5
Solid
Bioactive Small Molecule
Produktvorschläge

Produktvorschläge

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Dokumentation

Dokumentation

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Sonderangebote

Sonderangebote

For Research Use Only.