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R&D Systems™ Recombinant Human MSP/MST1 (Cys672Ala) Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
N.V.
Spezifikation
| Gen-ID (Entrez) | 4485 |
|---|---|
| Molekulargewicht | 53 kDa ( alpha-chain), 25 kDa (beta-chain) |
| Name | MSP/MST1 (Cys672Ala) |
| Menge | 10μg |
| Quelle | Chinese Hamster Ovary cell line,CHO-derived human MSP/MST1 protein Gln19-Arg483 (alpha) & Val484-Gly711 (Cys672Ala) (beta) |
Beschreibung
Measured by its ability to activate MSP R/Ron in MDA-MB-453 or T47D human breast cancer cells. 80 ng/mL of the recombinant human MSP (C672A) significantly induces phosphorylation of MSP R/Ron measured by the Human Phospho-MSP R/Ron DuoSet™ IC Kit (Catalog # DYC1947 ). Measured by its binding ability in a functional ELISA. When Recombinant Human MSPR/Ron Protein (Catalog #1947-MS) is represent at 100 ng/mL (100 μg/mL), The concentration of Recombinant Human MSP/MST1 that produces 50% optimal binding response is found to be 4-32 ng/mL.Spezifikation
| 4485 | |
| MSP/MST1 (Cys672Ala) | |
| Chinese Hamster Ovary cell line,CHO-derived human MSP/MST1 protein Gln19-Arg483 (alpha) & Val484-Gly711 (Cys672Ala) (beta) | |
| Disulfide-linked heterodimer | |
| Recombinant |
| 53 kDa ( alpha-chain), 25 kDa (beta-chain) | |
| 10μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution. | |
| Unconjugated | |
| >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |