R&D Systems™ Mouse Neurturin Recombinant Protein
Marke: R&D Systems™ 477-MN-025/CF
Weitere Details : Netto-Gewicht : 0.00010kg
BeschreibungMeasured by its ability to support the survival and stimulate neurite outgrowth of dissociated chick embryonic dorsal root ganglia (DRG) neurons. Davies, A.M. (1989) in Neurotrophic Factor Bioassay Using Dissociated Neurons, Nerve Growth Factor. Rush, R.A. (eds): John Willey and Sons, Ltd. 95. The ED 50 for this effect is 2-10 ng/mL. Also measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse GFR alpha-2/GDNF R alpha-2 Fc Chimera (Catalog # 429-FR ) at 1 µg/mL can bind Recombinant Mouse Neurturin with an apparent K D <3.0 nM.
|Lyophilized from a 0.2μm filtered solution in Acetonitrile and TFA with Trehalose.|
|11.7 kDa (monomer)|
|95%, by SDS-PAGE under reducing conditions and visualized by silver stain.|
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.|