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RepSox, Tocris Bioscience™

Potent and selective inhibitor of TGF-βRI

Marke:  Tocris (Bio-Techne) 374250

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13413534

  • 837.08 € / 50 Milligramm


Voraussichtlicher Liefertermin 02-05-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC 50 values are 4 and 23 nM for TGF-β type I receptor autophosphorylation and binding respectively). Selective for TGF-β type I receptor over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC 50 > 16 μM). Enhances the efficiency of cellular reprogramming; replaces Sox2 by inducing Nanog expression.
Spezifikation

Chemische Identifikatoren

446859-33-2
287.326
repsox, alk5 inhibitor ii, alk5 inhibitor, 2-3-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, tgf-beta ri kinase inhibitor ii, 2-3-6-methylpyridine-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, 2-3-6-methyl-2-pyridinyl-1h-pyrazol-4-yl-1,5-naphthyridine, 2-3-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, transforming growth factor-beta type i receptor kinase inhibitor ii, 2-5-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine
2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
C17H13N5
LBPKYPYHDKKRFS-UHFFFAOYSA-N
449054
CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4

Spezifikation

RepSox
446859-33-2
repsox, alk5 inhibitor ii, alk5 inhibitor, 2-3-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, tgf-beta ri kinase inhibitor ii, 2-3-6-methylpyridine-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, 2-3-6-methyl-2-pyridinyl-1h-pyrazol-4-yl-1,5-naphthyridine, 2-3-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine, transforming growth factor-beta type i receptor kinase inhibitor ii, 2-5-6-methylpyridin-2-yl-1h-pyrazol-4-yl-1,5-naphthyridine
CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
287.326
287.32
50mg
C17H13N5
LBPKYPYHDKKRFS-UHFFFAOYSA-N
2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
449054
>99%
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