missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ Rhesus IL-18, Recombinant Protein

Recombinant Protein

Marke:  Invitrogen™ RRMIL18I

Weitere Details : Netto-Gewicht : 0.80000kg

Artikelnummer. 11888811

  • 433.00 € / 20 Mikrogramm
Verfügbar ab: 16-04-2024
Sie sich ein, um den Lagerbestand zu sehen

Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!


Nur für Forschungszwecke. Die Anwendung muss den Produktanweisungen entsprechen.


Beschreibung

Beschreibung

Rhesus Interleukin 18 (IL-18) Recombinant Protein, RRMIL18I, from Invitrogen.

The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity. Mature rhesus macaque IL-18 was expressed in Pichia pastoris, X-33, GenBank Accession # AAK13416, amino acids 37 – 193. For protein verification, the expressed protein was N-terminal sequenced and begins with the following 10 amino acids: YFGKLESKLS. Purity is >95% by SDS-PAGE analyses. Activity: The biological activity of recombinant rhesus macaque IL-18 was determined by its ability to induce IFNg production from KG-1 cells in the presence of recombinant mouse IL-12. 270 pg/ml and 470 pg/ml of IFNg are induced by 20 ng/ml and 40 ng/ml of recombinant rhesus macaque IL-18, respectively. Use: For in vitro applications. A dose-response assay should be performed to determine the optimal concentration for specific experiments. Reconstitution and Dilution: Store lyophilized material at 4°C. Reconstitute in 0.5 ml of distilled or deionized water. Dilute in a buffer-containing carrier protein, aliquot, and store at or below -70°C, avoiding multiple freeze-thaw cycles. PBS with 1% BSA or a neutral media containing <10% FCS are suitable buffers.
Spezifikation

Spezifikation

Control, ELISA, Immunoprecipitation, Western Blot
574151
20μg
4°C
IL18; interleukin 18 (interferon-gamma-inducing factor); IGIF; IL-18; IL-1g; IL1F4; MGC12320; IL-1 gamma; interferon-gamma-inducing factor; interleukin 18; interleukin-1 gamma; interleukin-18
IL18
Unconjugated
Yeast
4° C
Recombinant
PBS with no preservative
Rhesus IL-18
Yeast
RUO
Rhesus IL-18
Rhesus Monkey
Rh
Recombinant
Lyophilized
purified
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote