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Invitrogen™ RIT1 Polyclonal Antibody
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Artikelnummer. 17208633 Alle ansehen Thermo Scientific Produkte
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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17208633 100 μL 100 Mikroliter
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Artikelnummer. 17208633 Lieferant Invitrogen™ Lieferanten-Nr. PA5115848

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Beschreibung

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RIT1.

Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64% amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100% conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen RIT1
Anwendungen Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 50% glycerol and 0.02% sodium azide
Gen RIT1
Gen-Zugriffsnummer P70426, Q92963
Gen-Alias GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; NS8; Ras like without CAAX 1; ras-like protein expressed in many tissues; Ras-like without CAAX 1; ras-like without CAAX protein 1; RGD1559874; RIBB; Ric-like, expressed in many tissues; RIT; RIT1; ROC1; si:ch211-93a2.3
Gensymbole RIT1
Wirtsspezies Rabbit
Immunogen A synthesized peptide derived from human RIT1(Accession Q92963), corresponding to amino acid residues R184-T219.
Reinigungsverfahren Affinity chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 19769, 499652, 6016
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Liquid
Isotype IgG
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