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Ro 3306, Tocris Bioscience™

Cyclin-dependent kinase (cdk) 1 inhibitor

Marke:  Tocris (Bio-Techne) 418150

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13414304

  • 1041.87 € / 50 Milligramm


Voraussichtlicher Liefertermin 20-02-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively). Induces G2/M phase cell cycle arrest and apoptosis. Downregulates the expression of antiapoptotic proteins such as Bcl-2 and survivin and enhances downstream p53 signaling in acute myeloid leukemia (AML).
Spezifikation

Chemische Identifikatoren

872573-93-8
351.442
cdk1 inhibitor iv, ro-3306, 5-6-quinolinylmethylene-2-2-thienylmethyl amino-4 5h-thiazolone, 5z-5-quinolin-6-ylmethylidene-2-thiophen-2-ylmethyl amino-1,3-thiazol-4-one, z-5-quinolin-6-ylmethylene-2-thiophen-2-ylmethylamino thiazol-4 5h-one, ro hplc, z-5-quinolin-6-ylmethylene-2-thiophen-2-ylmethyl amino thiazol-4 5h-one, 2-thiophen-2-ylmethyl-amino-5-1-quinolin-6-yl-meth-z-ylidene-thiazol-4-one, 5z-5-quinolin-6-yl methylidene-2-thiophen-2-yl methyl amino-4,5-dihydro-1,3-thiazol-4-one
(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one
C18H13N3OS2
XOLMRFUGOINFDQ-YBEGLDIGSA-N
11631681
C1=CC2=C(C=CC(=C2)C=C3C(=O)N=C(S3)NCC4=CC=CS4)N=C1

Spezifikation

Ro 3306
872573-93-8
cdk1 inhibitor iv, ro-3306, 5-6-quinolinylmethylene-2-2-thienylmethyl amino-4 5h-thiazolone, 5z-5-quinolin-6-ylmethylidene-2-thiophen-2-ylmethyl amino-1,3-thiazol-4-one, z-5-quinolin-6-ylmethylene-2-thiophen-2-ylmethylamino thiazol-4 5h-one, ro hplc, z-5-quinolin-6-ylmethylene-2-thiophen-2-ylmethyl amino thiazol-4 5h-one, 2-thiophen-2-ylmethyl-amino-5-1-quinolin-6-yl-meth-z-ylidene-thiazol-4-one, 5z-5-quinolin-6-yl methylidene-2-thiophen-2-yl methyl amino-4,5-dihydro-1,3-thiazol-4-one
C1=CC2=C(C=CC(=C2)C=C3C(=O)N=C(S3)NCC4=CC=CS4)N=C1
351.442
351.45
50mg
C18H13N3OS2
XOLMRFUGOINFDQ-YBEGLDIGSA-N
(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one
11631681
>98%
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