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S100A12 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 16630-1-AP-150UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886304

  • 329.85 € / 150 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.
Spezifikation

Spezifikation

S100A12
0.37 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P80511
CAAF1, CAGC, Calgranulin C, CGRP, EN RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100A12
Rabbit
IgG
150 μL
-20°C
Primary
6283
Immunohistochemistry (Paraffin)
Unconjugated
S100A12
Liquid
S100A12
S100A12 Fusion Protein Ag9961
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation