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SNX6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 10114-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886283

  • 112.71 € / 20 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
Spezifikation

Spezifikation

SNX6
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6P8X1, Q9UNH7
MSTP010, SNX6, sorting nexin 6, TFAF2, TRAF4 associated factor 2
Rabbit
IgG
20 μL
-20°C
Primary
362738, 58533, 72183
Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
SNX6
Liquid
Snx6
SNX6 Fusion Protein Ag0168
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation