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  5. Tocris Bioscience™ SP 600125

Tocris Bioscience™ SP 600125
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Codice prodotto. 18095862
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Menge:
10 mg
50 mg
Dimensione della confezione:
10 Milligramm
50 Milligramm
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Codice prodotto. Menge unitSize
18095862 10 mg 10 Milligramm
18095572 50 mg 50 Milligramm
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Codice prodotto. 18095862 Fornitore Tocris Bioscience™ N. del fornitore 1496/10

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Selective JNK inhibitor

SP 600125 is a selective JNK inhibitor. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes. Active in vivo. Exhibits reduced selectivity over other protein kinases under certain conditions. SP 600125 protects renal tubular epithelial cells from ischemia/reperfusion-induced apoptosis. Promotes chondrogenesis of bone mesenchymal stem cells by inhibition of TNF-α-induced inflammation. Adipogenesis from MSCs is also promoted by SP 600125. Essential component of medium for maintaining stem cells in naive pluripotent state.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 129-56-6
Summenformel Gehäuse C14H8N2O

Specifica

Chemischer Name oder Material SP 600125
Menge 10 mg
Formelmasse 220.23
Reinheit >98%
Molekulargewicht 220.231
Titolo del prodotto
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