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SPAG5 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 14726-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16883514

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 23-06-2021

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Beschreibung

Beschreibung

This antibody is specific to SPAG5.

SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein that is expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon and thymus. Localized specifically to spindle poles during prophase and throughout the spindle during metaphase and anaphase, SPAG5 is essential for proper spindle formation and is thought to be involved in the dynamic and functional regulation of mitotic spindles. Additionally, SPAG5 plays a role in sister chromatid cohesion and subsequent chromatid separation and, via its association with chromatids, is an important regulator of chromosome integrity. SPAG5 has a long stalk and a globular head domain through which if forms a homodimer that is characterized by aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
Spezifikation

Spezifikation

SPAG5
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q96R06
Astrin, DEEPEST, hMAP126, MAP126, SPAG5, sperm associated antigen 5
Rabbit
IgG
20 μL
-20°C
Primary
10615
Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Unconjugated
SPAG5
Liquid
SPAG5
SPAG5 Fusion Protein Ag6485
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate