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SSEA-1 Mouse, Alexa Fluor 647, Clone: MC480, BD
Mouse Monoclonal Antibody
325.00 €
Spezifikation
Antigen | SSEA-1 |
---|---|
Klon | MC480 |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Konjugat | Alexa Fluor 647 |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15891769
|
BD Biosciences
562277 |
25 Tests |
325.00 €
1 Stück |
Verfügbar ab: 15-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
The MC480 monoclonal antibody reacts with S tage- S pecific Entigen-1 (SSEA-1), which is a terminal carbohydrate epitope (3-fucosyl-N-acetyllactosamine or 3-FAL) on glycoproteins and lactose series glycolipids. SSEA-1 is related to Lewis blood group antigens and is found in a variety of embryonic and adult tissues and cancers. As its name implies, the expression of SSEA-1 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-1 is not found on embryonic stem (ES) cells, embryonic inner cell mass (ICM), or teratocarcinoma (embryonal carcinoma or EC) cells. As human EC and ES cells undergo differentiation, SSEA-1 expression is upregulated. In the adult, the same epitope is expressed as CD15 on granulocytes and monocytes, but not lymphocytes or dendritic cells. In the mouse, SSEA-1 is found on EC, ES, and primordial germ cells, 8-cell to blastocyst embryos, ICM, and on subpopulations of cells in the adult central nervous system, including stem cells. In contrast to the human, SSEA-1 expression is reduced as mouse EC and ES cells undergo differentiation.
Spezifikation
SSEA-1 | |
Flow Cytometry | |
Alexa Fluor 647 | |
RUO | |
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
MC480 | |
Monoclonal | |
Mouse | |
Human, Mouse | |
IgM κ | |
Affinity Purified | |
3-FAL, X-hapten, LeX antigen, CD15 |
For Research Use Only.