SUCLA2 Polyclonal Antibody, Invitrogen™

Beschreibung

Immunogen sequence: FGGIMRCDVI AQGIVMAVKD LEIKIPVVVR LQGTRVDDAK ALIADSGLKI LACDDLDEAA RMVVKLSEIV TLAKQAHVDV KFQLP Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.