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Sulindac, MedChemExpress

Product Code. 16478056
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Product Code. 16478056 Supplier Medchem Express Supplier No. HYB0008
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Verfügbar ab: 24-11-2026
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Beschreibung

MedChemExpress Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent.

Sulindac is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthritis of the spine, gouty arthritis. Sulindac, as an immunomodulatory agent, can downregulate PD-L1 through the blockade of NF-κB signaling and modulates the response of pMMR colorectal cancer (CRC) to anti-PD-L1 immunotherapy, inhibits the development and progression of colorectal cancer CRC. Sulindac also inhibits TGF-β1- induced epithelial-mesenchymal transition (EMT) and suppresses lung cancer cell migration and invasion via downregulation of SIRT1.

Spezifikation

Chemical Name or Material Sulindac
CAS 38194-50-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C20H17FO3S
Quantity 100 mg
Synonym MK-231
Solubility Information DMSO : 100 mg/mL (280.58 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(CC(C1=C2C=CC(F)=C1)=C(/C2=C/C3=CC=C(C=C3)S(C)=O)C)O
Molecular Weight (g/mol) 356.41
Formula Weight 356.41
Percent Purity 99.34%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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