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Tocris Bioscience™ TAK 960 hydrochloride
Potent and selective PLK1 inhibitor
N.V.
Spezifikation
| Produkttyp | TAK 960 hydrochloride |
|---|---|
| Beschreibung | TAK 960 hydrochloride |
| Molekulargewicht | 598.06 |
Beschreibung
Potent PLK1 inhibitor (IC50 values are 0.8, 16.9 and 50.2 nM for PLK1, PLK2 and PLK3 respectively). Exhibits >20-fold selectivity for PLK1 over FAK, MLCK and FES, and has minimal activity against a panel of 282 other kinases. Inhibits proliferation of a range of cancer cell lines in vitro and inhibits tumor growth of multiple human cancer cell xenografts in vivo. Orally bioavailable.Spezifikation
| TAK 960 hydrochloride | |
| TAK 960 hydrochloride | |
| 598.06 |
For Research Use Only