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Invitrogen™ Human Cytokeratin 18 Recombinant Protein

Recombinant Protein

Marke:  Invitrogen™ RP75534

Weitere Details : CAS : 69-74-9 Netto-Gewicht : 0.01000kg

Artikelnummer. 11584221

  • 684.00 € / 100 Mikrogramm
Verfügbar ab: 22-04-2024
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Beschreibung

Beschreibung

Cytokeratin 18 (human) Recombinant Protein, RP-75534, from Invitrogen.

Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas. Hepatocellular carcinomas express only cytokeratins 8 and 18. Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. This product contains purified recombinant human Cytokeratin-18 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
Spezifikation

Spezifikation

P05783
Control, Western Blot
3875
8
E. coli
-20°C, Avoid Freeze/Thaw Cycles
Ck18
KRT18
Unconjugated
E. coli
Liquid
purified
0.22mg/mL
tris HCl with 50% glycerol, 5mM EDTA and no preservative; pH 8
Human Cytokeratin 18
100μg
N/A
RUO
Human Cytokeratin 18
Human
Hu
Recombinant
Recombinant
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote