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TNF Rat anti-Mouse, PE-Cy7, Clone: MP6-XT22, BD
Rat Monoclonal Antibody
206.00 € - 487.00 €
Spezifikation
| Antigen | TNF |
|---|---|
| Klon | MP6-XT22 |
| Konzentration | 0.2mg/mL |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15890709
|
BD Biosciences
561041 |
25 μg |
206.00 €
1 Stück |
Verfügbar ab: 22-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
12683356
|
BD Biosciences
557644 |
0.1 mg |
487.00 €
1 Stück |
Verfügbar ab: 22-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
The MP6-XT22 antibody specifically binds to mouse Tumor Necrosis Factor (TNF, also known as TNF-α). TNF is produced by many activated cell types including monocytes, macrophages, astrocytes, granulocytes, mast cells, T and B lymphocytes, NK cells, keratinocytes, fibroblasts, adipocytes, and certain tumor cells. Activated cells express type II transmembrane TNF glycoproteins that associate as homotrimeric complexes. After enzymatic cleavage, the extracellular regions of membrane TNF are shed as soluble homotrimers. TNF is a potent multifunctional cytokine that can exert regulatory and cytotoxic effects on a wide range of normal lymphoid and non-lymphoid cells and tumor cells. Although TNF serves as a primary mediator in protective immune responses against microbial and viral pathogens, it can also drive systemic pathophysiologic responses including septic shock, cachexia and autoimmune diseases. Mouse TNF exerts its biological activities by binding and signaling through cell surface membrane Type I and Type II TNF Receptors (aka, TNFRI/CD120a and TNFRII/CD120b, respectively).
Spezifikation
| TNF | |
| 0.2mg/mL | |
| Monoclonal | |
| Rat | |
| Mouse | |
| Recombinant Mouse TNF | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| MP6-XT22 | |
| Flow Cytometry | |
| PE-Cyanine7 | |
| RUO | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
For Research Use Only.