missing translation for 'onlineSavingsMsg'
Learn More

Tocris Bioscience™ Topiramate

GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV

N.V.

Spezifikation

Reinheit >99%
Gen-Alias Topamax
Produkttyp Topiramate
Molekulargewicht 339.36
Hemmstoffe Topiramate
Mehr Spezifikationen ansehen

Beschreibung

Beschreibung

Anticonvulsant. Antagonizes GluK1 (formerly GluR5) kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.

Deuterated analog also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Spezifikation

Spezifikation

>99%
Topiramate
Topiramate
Topamax
339.36
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen

For Research Use Only