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Tocris Bioscience™ Topiramate

GluR5 antagonist; inhibits carbonic anhydrase (CA) II and IV

Marke:  Tocris Bioscience™ 362010

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 13413304

  • 139.05 € / 10 Milligramm


Voraussichtlicher Liefertermin 20-02-2019
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Beschreibung

Beschreibung

Anticonvulsant. Antagonizes GluR5 kainate receptors (IC50 = 0.46μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
Spezifikation

Spezifikation

Topiramate
>99
10mg
Topiramate
339.36
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