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USP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 10473-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886873

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 25-06-2021

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Beschreibung

Beschreibung

USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. It is involved in uchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the uchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Spezifikation

Spezifikation

USP5
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P45974, P56399
Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5
Rabbit
IgG
20 μL
-20°C
Primary
22225, 297593, 8078
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
USP5
Liquid
USP5
USP5 Fusion Protein Ag0770
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Mouse, Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate