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Y 134, Tocris Bioscience™

Selective estrogen receptor modulator (SERM), selective for ERα

Marke:  Tocris (Bio-Techne) 267650

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13411714

  • 780.76 € / 50 Milligramm


Voraussichtlicher Liefertermin 30-04-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Selective estrogen receptor modulator (SERM) that displays selectivity for ERα over ERβ (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.
Spezifikation

Chemische Identifikatoren

849662-80-2
472.603
d0y4nj, 6-hydroxy-2-4-hydroxyphenyl benzo b thiophen-3-yl 4-4-isopropylpiperazin-1-yl phenyl methanone, 6-hydroxy-2-4-hydroxy-phenyl-benzo b thiophen-3-yl-4-4-isopropyl-piperazin-1-yl-phenyl-methanone, 6-hydroxy-2-4-hydroxyphenyl benzo b thien-3-yl-4-4-1-methylethyl-1-piperazinyl phenyl methanone, 6-hydroxy-2-4-hydroxyphenyl benzothiophen-3-yl-4-4-isopropylpiperazin-1-yl phenyl methanone, 2-4-hydroxyphenyl-3-4-4-propan-2-yl piperazin-1-yl phenyl carbonyl-1-benzothiophen-6-ol
[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methanone
C28H28N2O3S
LQEOPHGPHCWOAC-UHFFFAOYSA-N
11784736
CC(C)N1CCN(CC1)C2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O

Spezifikation

Y 134
849662-80-2
d0y4nj, 6-hydroxy-2-4-hydroxyphenyl benzo b thiophen-3-yl 4-4-isopropylpiperazin-1-yl phenyl methanone, 6-hydroxy-2-4-hydroxy-phenyl-benzo b thiophen-3-yl-4-4-isopropyl-piperazin-1-yl-phenyl-methanone, 6-hydroxy-2-4-hydroxyphenyl benzo b thien-3-yl-4-4-1-methylethyl-1-piperazinyl phenyl methanone, 6-hydroxy-2-4-hydroxyphenyl benzothiophen-3-yl-4-4-isopropylpiperazin-1-yl phenyl methanone, 2-4-hydroxyphenyl-3-4-4-propan-2-yl piperazin-1-yl phenyl carbonyl-1-benzothiophen-6-ol
CC(C)N1CCN(CC1)C2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O
472.603
472.6
50mg
C28H28N2O3S
LQEOPHGPHCWOAC-UHFFFAOYSA-N
[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]methanone
11784736
>98%
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