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Thermo Scientific Chemicals 2',3'-Dideoxycytidin, 98 %

Catalog Number 11332906
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Menge:
50 mg
250 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
7481-89-2
C9H13N3O3
211.22
MFCD00012188
WREGKURFCTUGRC-KGQMAECUNA-N
zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one
24066
CHEBI:10101
NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
7481-89-2
C9H13N3O3
211.22
MFCD00012188
WREGKURFCTUGRC-KGQMAECUNA-N
zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one
24066
CHEBI:10101
NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Chemischer Name oder Material 2′,3′-Dideoxycytidine
Schmelzpunkt 216°C to 220°C
Verpackung Glasflasche
Menge 250 mg
Beilstein 654956
Löslichkeitsinformationen Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C).
IUPAC-Name 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
Formelmasse 211.22
Reinheit (%) ≥98%
Physikalische Form Fest

RUO – Research Use Only

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