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2'-Fluoro-iBu-G Phosphoramidite, standard grade, serum vial bottle

Artikelnummer. 30054752 Alle ansehen Thermo Scientific Produkte
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Artikelnummer. 30054752 Lieferant Thermo Scientific Lieferanten-Nr. 27160702
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Verfügbar ab: 17-07-2026
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Beschreibung

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:

  • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula—C44H53FN7O8P
  • Base—G
  • Base Protection—iBu
  • Formula weight—857.4 g/mol
  • CAS number—144089-97-4
  • HPLC purity—>98%
  • 31P NMR purity—≥98%
TRUSTED_SUSTAINABILITY

Spezifikation

Format Pulver
Zur Verwendung mit (Geräte) AKTA Synthesegeräte, Applied Biosystems Synthesegeräte
Produkttyp 2in-Fluoro-iBu-G CEP
Inhalt und Lagerung Im Tiefkühlgerät lagern (bei oder unter -20 °C).
Nukleosidtyp Guanosine (G)
Reagenzienfunktionen 2in-Fluoro modified
Versandbedingung Raumtemperatur
Reinheit 98%
Reagenztyp Phosphoramidit
Güte Standard
Nukleinsäuretyp RNA
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Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.

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