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Invitrogen™ 4EBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA582838
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Beschreibung
Immunogen sequence: PGGTRIIYDR KFLMECRNSP VTKTPPRDLP TIPGVTSPSS DEPPMEASQS HLRNSPEDKR AGGEESQFEM DI Highest antigen sequence indentity to the following orthologs: Mouse - 89%, Rat - 92%.
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Spezifikation
| 4EBP1 | |
| Polyclonal | |
| Unconjugated | |
| EIF4EBP1 | |
| 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 116636, 13685, 1978 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q13541, Q60876, Q62622 | |
| EIF4EBP1 | |
| Recombinant protein corresponding to Human EIF4EBP1. Recombinant protein control fragment (Product #RP-93944). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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