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Invitrogen™ Acinus Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA519938
This item is not returnable.
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Description
In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is K562 cell lysate. PA5-19938 can be used with blocking peptide PEP-0063.
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
Specifications
| Acinus | |
| Polyclonal | |
| Unconjugated | |
| ACIN1 | |
| 2610036I19Rik; 2610510L13Rik; Acin1; ACINUS; acinusL; acinusS; Acn; apoptotic chromatin condensation inducer 1; apoptotic chromatin condensation inducer in the nucleus; C79325; DKFZp667N107; fSAP152; functional spliceosome-associated protein 152; KIAA0670; mKIAA0670 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 22985 | |
| Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q9UKV3 | |
| ACIN1 | |
| A peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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