Invitrogen™ Acryloyl-X, SE, 6-((Acryloyl)amin)hexansäure, Succinimidylester

6-([Acryloyl]Amino)Hexansäure, Succinimidylester (Acryloyl-X, SE)

Acryloyl-X, SE (6-((acryloyl)amino)hexanoic acid, succinimidyl ester) is an amine-reactive molecule that enables crosslinking of acrylamide to proteins and other biomolecules containing amines. The succinimidyl ester of acryloyl-X covalently reacts with amines of proteins, amine-modified nucleic acids, and other biomolecules to yield acrylamides that can be copolymerized into polyacrylamide matrices or on surfaces, such as in microarrays and in biosensors. For instance, acryloyl-X, SE is used to prepare streptavidin acrylamide (Cat. No. S21379), which can copolymerize with acrylamide on a polymeric surface to create a uniform monolayer of immobilized streptavidin for binding to biotinylated ligands such as hybridization probes, enzymes, antibodies, and drugs.