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  7. Alendronate sodium trihydrate, 97%

Alendronate sodium trihydrate, 97%

Artikelnummer. 15493999
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Artikelnummer. 15493999 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J61397.03
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Beschreibung

CAS: 121268-17-5 | C4H18NNaO10P2 | 325.122 g/mol

Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

Solubility
Soluble in water at 10mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 121268-17-5
Summenformel C4H18NNaO10P2
Molekulargewicht (g/mol) 325.122
MDL-Nummer MFCD01748233
InChI-Schlüssel DCSBSVSZJRSITC-UHFFFAOYSA-M
Synonym alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan
PubChem CID 23681107
ChEBI CHEBI:2566
IUPAC-Name sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]

Specifications

Chemischer Name oder Material Alendronate sodium trihydrate
Farbe Weiß
Menge 1 g
Merck Index 14,229
Löslichkeitsinformationen Soluble in water at 10mg/ml
Formelmasse 325.12 (271.08 Anhydrous)
Reinheit (%) 97%
Physikalische Form Fest

RUO – Research Use Only

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