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Invitrogen™ alpha Actinin 3 Polyclonal Antibody

Beschreibung
Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, JC, PC-12. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (94%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele.
Spezifikation
Spezifikation
| Antigen | alpha Actinin 3 |
| Anwendungen | Immunoprecipitation, Western Blot |
| Klassifikation | Polyclonal |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gen | Actn3 |
| Gen-Zugriffsnummer | O88990, Q08043 |
| Gen-Alias | actinin alpha 3; actinin alpha 3 (gene/pseudogene); Actinin alpha3; actinin, alpha 3; Actinin-alpha3; ACTN3; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 3; alpha-Actinin3; Alpha-actinin-3; alphaActinin-3; F-actin cross-linking protein |
| Gensymbole | Actn3 |
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