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Thermo Scientific Chemicals Alpha-Melanozyten-stimulierendes Hormonamid

Artikelnummer. 15496309
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Menge:
1 mg
5 mg
Packungsgröße:
1 Milligramm
5 Milligramm
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Artikelnummer. 15496309

Marke: Thermo Scientific Chemicals J64310.M

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Endogener Melanocortin-Rezeptor-Agonist. Entzündungshemmendes Peptid; antagonisiert entzündungsfördernde Mediatoren, einschließlich TNF-α IL-6 und NO und induziert das entzündungshemmende Zytokin IL-10.

alpha-Melanocyte Stimulating Hormone amide is an endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-α, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 581-05-5

Specifications

Inhalt und Lagerung Aufbewahrung bei -20 °C
Format Fest
Summenformel C77H109N21O19S
MDL-Nummer MFCD00133062
InChI-Schlüssel WHNFPRLDDSXQCL-PDEGJNOBSA-N
SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)NC(CC1=CN=CN1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
IUPAC-Name (4S)-4-[(1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl)carbamoyl]-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid
Menge 1 mg
Molekulargewicht (g/mol) 1664.91

RUO – Research Use Only

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