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Beschreibung
This antibody stains the aorta only.
Among the six actin isoforms described in mammals, two are found in virtually all cells (b- and g-cytoplasmic), two are detected in smooth muscle cells (a- and g-smooth muscle) and two are present in striated muscles, one predomitly in skeletal (a-skeletal) and one in cardiac (a-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.
Spezifikation
Spezifikation
| Antigen | Alpha SMA |
| Anwendungen | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Klassifikation | Polyclonal |
| Konzentration | 0.35 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gen | ACTA2 |
| Gen-Zugriffsnummer | P62736, P62737, P62738 |
| Gen-Alias | a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 Smooth muscle Actin Specific, Actin, aortic smooth muscle, Alpha actin 2, Alpha SMA, Alpha SMA Specific, a-SMA, smooth muscle actin, alpha SMA |
| Gensymbole | ACTA2 |
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