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Aurintricarbonsäure Triammoniumsalz, Thermo Scientific Chemicals

Product Code. 11478366
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Menge:
10 g
50 g
250 g
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10 Gramm
250 Gramm
50 Gramm
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Product Code. 11478366

missing translation for 'mfr': Thermo Scientific Alfa Aesar A15401.30

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Description

CAS: 569-58-4 | C22H23N3O9 | 473.438 g/mol

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Es ist ein potenter Inhibitor von Ribonuklease und Topoisomerase II, indem es die Bindung der Nukleinsäure an das Enzym verhindert. Es stimuliert Tyrosinphosphorylierungsprozesse, einschließlich des Jak2/STAT5-Signalwegs in NB2-Lymphomzellen, ErbB4 in Neuroblastomzellen und MAP-Kinasen, SHC-Proteine, Phosphoinositid-3-Kinase und Phospholipase C in PC12-Zellen. Aurintricarbonsäure hemmt die Apoptose in vielen Zelltypen.

Löslichkeit
In Wasser löslich (800 g/l).

Hinweise
Kühl lagern. Behälter an einem trockenen und gut belüfteten Ort dicht verschlossen halten. Von starken Oxidationsmitteln fernhalten.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 569-58-4
Summenformel C22H23N3O9
Molekulargewicht (g/mol) 473.438
MDL-Nummer MFCD00040925
InChI-Schlüssel AIPNSHNRCQOTRI-UHFFFAOYSA-N
Synonym Aurintricarboxylic acid triammonium salt
PubChem CID 54729869
ChEBI CHEBI:87398
IUPAC-Name triazan5-[(3-Carboxy-4-Oxidophenyl)-(3-Carboxy-4-Oxocyclohexa-2,5-dien-1-Yliden)Methyl]-2-Oxidobenzoat
SMILES C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Specifications

Chemischer Name oder Material Aluminon
Schmelzpunkt 220°C to 225°C (decomposition)
Merck Index 14,322
Löslichkeitsinformationen Soluble in water(800g/L).
Formelmasse 473.44
Geruch Geruchsneutral
pH 5.3
Menge 250 g

RUO – Research Use Only

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