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AM 580, Tocris Bioscience™

Catalog Number 18095782
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Menge:
10 mg
50 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
102121-60-8
C22H25NO3
351.45
MFCD00673916
SZWKGOZKRMMLAJ-UHFFFAOYSA-N
2126
CHEBI:64210
4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-amido)benzoic acid
CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
102121-60-8
C22H25NO3
351.45
MFCD00673916
SZWKGOZKRMMLAJ-UHFFFAOYSA-N
2126
CHEBI:64210
4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-amido)benzoic acid
CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O

Beschreibung

Retinoic acid analog; RARα agonist

AM 580 is an analog of retinoic acid that acts as a selective RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFNγ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro.

AM 580 synthesized to Ancillary Material Grade also available.

Chemischer Name oder Material AM 580
Menge 10 mg
Synonym unii-vz5s5g9zfz, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl carbonyl amino benzoic acid, vz5s5g9zfz, chembl69367, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido benzoic acid, benzoic acid,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl aminobenzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carboxamido benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino benzoic acid, benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino
Formelmasse 351.44
Reinheit (%) >98%
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