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AMG 487, MedChemExpress
Description
AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
Specifications
Specifications
| Chemischer Name oder Material | AMG 487 |
| CAS | 473719-41-4 |
| Farbe | Yellow |
| Hinweise zur Reinheitsqualität | Research |
| Summenformel | C32H28F3N5O4 |
| Menge | 10 mg |
| Löslichkeitsinformationen | DMSO : ≥ 41 mg/mL (67.93 mM) |
| SMILES | O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5 |
| Molekulargewicht (g/mol) | 603.59 |
| Formelmasse | 603.59 |
| Show More |
Research purposes only
Product Title
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